
This umbrella review protocol has been registered with PROSPERO CRD42017068357. It will also help set the future research agenda in this field and guide the development of interventions. This will yield important information for policymakers, practitioners and researchers at the local, national and international level. Our umbrella review protocol provides a robust method to systematically appraise the evidence in this field, using new conceptual models derived specifically to address the study question.
#MACRO ECONOMIC ENVIRONMENT PRO#
Data will be extracted using a standardized pro forma, and the findings will be synthesized into a conceptual framework to address our review aim.

Six databases will be searched using tailored versions of our piloted search strategy to locate relevant reviews. Secondary outcomes will include health inequalities by gender, ethnicity or socio-economic status.

Primary outcomes will include but are not limited to morbidity, mortality, prevalence and incidence of conditions and life expectancy. Reviews of studies with and without controls will be included both association and intervention studies will be included. Reviews will be included if they meet the Database of Abstracts and Reviews of Effects criteria for systematic reviews. We will identify relevant systematic reviews using search terms derived from the Journal of Economic Literature classification. This protocol details the methods for an umbrella review to explore the macro-economic factors, strategies, policies and interventions that affect health outcomes and health inequalities. We conceptualise the economy as a complex system made up of underlying approaches, regulation from institutions, markets, finance, labour, the public-private balance as well as production and distributional effects, which collectively impact on health through the effect of moderators. The economic determinants of health have been widely recognised as crucial factors affecting health however, to date, no comprehensive review has been undertaken to summarise these factors and the ways in which they can influence health.
